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Endoglin 抗体 (FITC)

This anti-Endoglin antibody is a 小鼠 单克隆 antibody detecting Endoglin in FACS. Suitable for 人 和 马.
产品编号 ABIN319843
发货至: 中国

Quick Overview for Endoglin 抗体 (FITC) (ABIN319843)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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人, 马

宿主

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小鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

SN6
  • 特异性

    SM1177F recognizes the CD105 cell surface antigen.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Partially purified cell membrane antigens from fresh leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/NS1/1-Ag4-1 myeloma cell line

    亚型

    IgG1
  • 应用备注

    Flow cytometry (use 10 μL of neat antibody to label 10^6 cells in 100 μL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as a preservative and 1 % BSA as a stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Endoglin (ENG)

    别名

    CD105 / Endoglin

    背景

    CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2. CD105 is a glycoprotein homodimer of 95 kD subunits. CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.Synonyms: END, ENG, HHT1, ORW, ORW1

    基因ID

    9606

    UniProt

    P17813
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